JPIAMR – InnovaResistance: Innovative approaches to address antibacterial resistance

By Feb.11, 2014

Funding opportunity

Title

InnovaResistance: Innovative approaches to address antibacterial resistance

Funder

Joint Programming Initiative on Antimicrobial Resistance (JPIAMR)

Deadline

14th March 2014 (for pre-proposals)

Value

Total funding of €14.5m is available under this call

Aim

The primary aim of this first joint call of JPIAMR is to combine the resources, infrastructures, and research strengths of multiple countries in order to overcome antibiotic resistance. The goal is to foster multinational translational research collaborations that can accomplish more than individual countries working independently, leading to improved control of bacterial infections.

It is expected that through international collaborations that combine complementary and synergistic research strengths, this JPIAMR call will facilitate the generation and application of new approaches to overcome antibiotic resistance.

The call will cover research addressing the following topics:

  • Re-evaluation of existing anti-microbial compounds either alone or in combination with other drugs, immune-modulators or anti-bacterial approaches.
  • Identification of new bacterial targets and/or therapeutic compounds in combination with point-of-care companion diagnostics where relevant.
  • Discovery and implementation of novel therapies to overcome known antimicrobial resistance mechanisms and restore susceptibility to conventional antibiotics. Examples might include studies on novel enzyme or efflux pump inhibitors, as well as studies aimed at understanding and overcoming the mechanisms controlling   the generation of resistance.
  • Strategies for optimization of drug use, dosage and delivery of new drugs or drug combinations.
  • Strategies to inhibit or reduce the acquisition of resistance such as single molecular agents effective against multiple targets as well as therapeutics that enhance immune pathogen elimination, disrupt colonization, biofilm development, and virulence.

Length

Up to 3 years

Eligibility

Applicants must adhere to the specific regulations of the national funding organisations and it is highly recommended for applicants to contact their national contact person prior to submitting. Each transnational consortium submitting a proposal must involve:

  • A minimum of 3 eligible participants from three different countries participating in the call.
  • A maximum of 6 project participants from 3 to 6 countries.
  • Project participants not eligible to be funded (e.g. from non-funding countries or not fundable according to national/regional regulations of the participating funding countries) may be involved in projects if they secure their own funding and if their expertise is indispensable for reaching the objectives. The consortia should always consist of a majority of funded project participants.
  • Project participants not eligible to be funded cannot be consortium coordinators and must accept all JPIAMR rules and guidelines just as funded members.

Details

http://www.jpiamr.eu/activities/open-call/